Cybersecurity aggregates are numerical data obtained by aggregation on features along a database of cybersecurity reports. These aggregates are obtained by integration of time-stamped tables using some recent results of non-standard calculus. Time-series of aggregates are shown to contain relevant information about the concrete system dealt with. Trend time series is also forecasted using known data-driven methods. Although absolute forecasting of trend time series is not obtained, a directional forecasting of trend time series is achieved thence validated by means of (...) a rolling cross validation scheme on a public database of Scareware reports. (shrink)

Volume 24, Issue 7, July 2024, Page 6-12.

By Olga Campos, Mª Ángeles Arráez, Miguel Moreno, Francisco Lara, Pedro Francés, and Javier Rodríguez Alcázar.

Rationale, aims and objectives Given the increasing prevalence of cataract and demand for cataract extraction surgery, patients must often wait to undergo this procedure. We validated a previously developed priority scoring system in terms of clinical variables, pre-intervention health status, appropriateness of surgery and gain in visual acuity (VA) and health-related quality of life (HRQoL).Methods Explicit prioritization criteria for cataract extraction created by a variation of the Research and Development (RAND) and University of California Los Angeles appropriateness methodology were retrospectively (...) applied to a prospective cohort of 5257 patients on waiting lists to undergo cataract by phacoemulsification at 17 hospitals in Spain. Demographic data, clinical data and data related to surgical technique were collected by trained ophthalmologists. Patients were evaluated by their ophthalmologist before the intervention and 6 weeks afterward. They also completed, by mail, the Visual Function Index (VF-14) before the intervention and 3 months afterward.Results High-priority patients experienced greater improvement in VA and HRQoL than those classified as intermediate or low-priority (P < 0.0001), even after adjusting by VA and the VF-14 score at baseline. The time to intervention was the same for high-priority patients as it was for intermediate and low-priority patients.Conclusions The priority score we developed identified patients most likely to experience the greatest improvements from cataract extraction. Use of this tool could provide a fairer and more rational way to prioritize patients for cataract extraction. (shrink)

Agradezco sinceramente la oportunidad que se me brinda para dar mi opinión, para contar mis impresiones, para ofrecer mis reflexiones o para, simplemente, expresar mis certidumbres y mis dudas, que de todo hay en un mundo tan complejo como es el de la sanidad. Hace casi diez años que me senté por primera vez en el Consejo Interterritorial del Sistema Nacional de Salud. Gobernaba por entonces en España el PSOE y lo haría hasta Marzo de 1996, era Ministra de Sanidad (...) y Consumo una persona a la que quiero mucho y respeto más, Mª Ángeles Amador. Conoceré luego a cuatro ministros más, J.M. Romay, C. Villalobos, A. Pastor y E. Salgado.…. (shrink)

La traducción que al inglés hace el ilustre profesor norteamericano Harold Raley (cuya filosofía sigue a Ortega y a Marías) resulta excelente. El profesor Harold Cecil RALEY nació el año 1934 en el Estado de Alabama (USA), en cuya Universidad se doctoró en Lenguas y Literaturas Románicas, y quiso especializarse en la obra de José Ortega y Gasset. Casado y padre de varios hijos, ha sido catedrático de Lengua y Literatura españolas de la Universidad del Estado de Oklahoma desde 1964; (...) también catedrático y decano de Bellas Artes y Humanidades en la Houston Baptist University (nombrado por ella Distinguished Professor). Entre otros libros, es autor de los siguientes: "Ortega y Gasset, filósofo de la unidad europea" (Prólogo de Julián Marías. Revista de Occidente. Madrid, 1977; edición inglesa: "José Ortega y Gasset, the Philosopher of European Unity". The University of Alabama Press. USA, 1971); "La visión responsable. La filosofía de Julián Marías" (Prólogo de José Luis Pinillos. Espasa-Calpe. Madrid, 1977; edición inglesa: "Responsible Vision: The Philosophy of Julián Marías". The American Hispanist. Clear Creek, Indiana. USA, 1980); "Julián Marías. Una filosofía desde dentro" (Alianza Editorial. Madrid, 1997; edición inglesa: "A Watch over Mortality: the Philosophical Story of Julián Marías". The State University of New York Press. USA, 1997); "El espíritu de España" (Prólogo de Julián Marías. Alianza Editorial. Madrid, 2003; edición inglesa: "The Spirit of Spain". Halcyon Press. Houston. USA, 2002); "The Light of Eden. A Christian Worldview" (John M. Hardy Publishing. Houston. USA, 2008); "Language Oddities. Quirks and Curiosities of English and Other Languages" (Kingsle. Houston. USA, 2011); "Louisiana Rogue. The Life and Times of Pierre Prospère-Tourmoulin translated by Peter Tourmoulin" (Lamar University Press. Beaumont. USA, 2013); "The Unknown God: Mysteries of Deity, Time, Space, and Creation" (Charleston, SC, USA, 2011. También es autor de más de un centenar de estudios y artículos sobre temas filosóficos y literarios. Además ha traducido al inglés algunos de los libros de Julián Marías. (shrink)

Desde que se inicia el confinamiento hasta la actualidad, se dispara la inseguridad en el sector económico en general, situando en un estado aún más crítico a los colectivos sociales más vulnerables como las mujeres. Pondremos nuestro punto de mira y objetivo en el trabajo social y de inserción desarrollado con las mujeres migrantes riojanas durante la pandemia. Para ello, se llevará a cabo una revisión y análisis de datos socioeconómicos en base a las tasas de paro y de empleo (...) solicitados a fecha de 31 de diciembre 2020, considerando la proyección para el año 2021. A su vez, se revisará el trabajo de intervención desarrollado para dicho colectivo. (shrink)

The aim of this work is to analyse the concept of semi-sentence from a linguistic, formal and computational point of view. A semi-sentence can be characterised as a sentence which, from a grammatical perspective, is neither absolutely correct nor incorrect . This study focuses on: - a characterisation of the semi-sentences in the setting of the grammar of a language. This study will help to analyse in depth the concept of grammaticality [3]; - the correlate of semi-sentences in formal languages, (...) i.e., semi-strings, which arise from applying productions that deviate from that which is strictly permitted by the rules of grammar [6]; - a Prolog program for handling semi-grammaticality in a computational manner [2]. (shrink)

Knowledge of diverse sexual motivations can have profound implications for our comprehension of the causes, correlations, and consequences of sexual behavior. This study had two objectives: on the one hand, to determine the different motives why young Spanish university students have sex and their relationship with different sociodemographic and psychosexual variables and sexual behavior; on the other hand, to review and improve the psychometric properties of the Sexual Motivations Scale and validate it in Spanish. Participants were 805 university students of (...) both sexes, aged between 18 and 26 years, who completed a battery of online questionnaires. Significant associations were found between young people's sexual motives, especially the motives of coping, peer pressure, and enhancement, the sociodemographic variables, sexual behavior, and psychosexual variables. Also, a new structure of the Sexual Motivations Scale was proposed, with the elimination of the factor of Self-Affirmation. The discussion highlights the relevance of the results obtained due to their implications in the promotion of sexual health, in addition to achieving the first instrument validated in Spanish for the evaluation of sexual motivations. (shrink)

Sabemos que desde una perspectiva científica, al activar determinados estímulos musicales se produce una activación a nivel cerebral. Con las agrupaciones musicales escolares se requiere previamente activar las técnicas de audición e interpretación de forma individual para lograr en el grupo, aptitudes motoras, perceptivas, cognitivas y activar procesos afectivos y de socialización. De esta forma, la atención a la diversidad no quedaría excluida. La música, en definitiva, favorece el desarrollo de la persona en todas sus dimensiones, lo cual redunda en (...) una mejora de la calidad de vida y es un gran avance a nivel personal, familiar, escolar, clínico y social. La actividad musical es como un sistema de introducción en el marco cultural insustituible. (shrink)

Este trabajo se inscribe en una revisión in progress del Derecho antidiscriminatorio moderno que las autoras vienen efectuando desde hace más de tres lustros. En la primera parte del mismo se examinan los textos de una f ilósofa política y de dos juristas esta- dounidenses (I. M. Young, C. A. MacKinnon y K. Crensahw) que inspiran la propuesta de un concepto de discriminación y de una visión de la interseccionalidad basados en el reconocimiento de los sistemas de opresión. La segunda (...) parte se centra en el análisis del concepto de discriminación múltiple o interseccional propuesto por la doctrina jurídica española a partir de la jurisprudencia referida al caso de una mujer (“La Nena”) casada por el rito gitano que ve denegada su pensión de viudedad. A partir de lo anterior, el trabajo concluye con una serie de propuestas entre las que destacan las referidas a la necesidad de evitar que el discurso sobre la interseccionalidad disuelva la identidad política de los grupos en la individualidad, refuerce el sistema sexo-género y consolide un Derecho antidiscriminatorio de corte excesivamente jurisprudencial. (shrink)

En el presente estudio analizaremos la expresión del conflicto en el lenguaje, donde la lucha palabra-letra impregna la teoría agónica del lenguaje y marca la trascendencia sobre la relación historia-intrahistoria. Asimismo, presentaremos la dimensión creadora del lenguaje, relevante desde el Unamuno contemplativo, y el papel desempeñado por el diálo go a la hora de expresar los dos poíos del conflicto, agónico y contem plativo.

This book brings together previously unpublished work which looks at issues concerning the foundations and applications of a prominent branch of virtue epistemology: “performance-based epistemology”. The chapters in Part I examine some foundational issues in the conceptual framework of PBE: the relations between apt success and luck; the connection between aptness and a safety condition for knowledge; the fallibility of competences; the kind of reliability needed for knowledge and justification; the nature of epistemic agency; and some ways of enriching the (...) basic conceptual framework of PBE. The chapters in Part II discuss the application of PBE to outstanding problems in contemporary epistemology, such as the nature of a priori intuition; internalist objections to epistemic externalism; the roles that epistemic agency is meant to play in the acquisition of knowledge; the value of second-order reflection; the nature of some epistemic incompetences; and the problem of epistemic circularity. (shrink)

Las redes sociales se han convertido en el elemento estrella de la red en los últimos años. A través de ellas miles de personas comparten informaciones con otros con los que tienen algún interés común. El problema actual de algunas de ellas radica en la dificultad a la hora de coordinar esos recursos aportados, una labor que se complica a la hora de intentar recuperar todos esos datos vertidos. Desde el Laboratorio de Innovación en Tecnologías de la Información se ha (...) desarrollado, tras ocho años de trabajo, un software para clasificar, organizar y poner en común los recursos aportados por los miembros de una red orientada al recurso. Como desarrollo de este trabajo ha nacido MARIA, un buscador de recursos formativos orientados a niños con edades comprendidas entre 8 y 12 años, nutrido de la colaboración de personas adultas que conforman esa red social. A lo largo de este artículo se detallan las características y utilidades de este nuevo buscador, basado en una red social en la que sus miembros aportan recursos de un modo solidario y desinteresado, consiguiendo un sistema fácil y eficaz para ser utilizado por todos aquellos que lo necesiten. (shrink)

In this paper, I develop a problem I call the “Conditional Position Problem” that arises for Ernest Sosa’s externalist epistemology. The problem is that, due to a phenomenon of epistemic circularity, one is unable to attain the reflective knowledge that one is justified in believing that perception is reliable, and is confined to the merely conditional position that one is so justified if perception is reliable. The problem is similar but different from a problem that Barry Stroud has tried to (...) formulate. However, because of space limitations I cannot explain in detail what makes the two problems different. The structure of the paper is as follows: first, I explain the structural features of Sosa’s epistemology that allow the problem to arise; I also describe the normative task that is thwarted by the Conditional Position Problem; then I expound the problem itself. I proceed to examine one response that Sosa can give based on a simple inferential manoeuvre and explain why that response fails; then I examine another response he can give based on a complex form of self-support, and explain why this response also fails. I conclude explaining why the problem I present is specifically a problem for externalism. In an appendix, I very briefly describe what I take to be the main reason that justifies my claim that Stroud's problem is not the same as the problem I develop. (shrink)

La presente nota crítica del libro de Juan Comesaña Being Rational and Being Right se divide en tres secciones. La sección I describe las caracteristicas fundamentales del “Experiencialismo”, que es la teoría de la racionalidad básica desarrollada y defendida a lo largo del libro; la sección II indica brevemente el contenido de los capítulos; y la sección III articula y discute una cuestión problemática acerca de cómo el Experiencialismo interactúa con el debate liberalismo/conservadurismo en la teoría de la justificación.

The proteins encoded by early region 1 A (E1A) of human adenoviruses (Ad) modulate the expression of both adenovirus genes and various host cell genes. With these transcription‐regulating properties the E1A proteins redirect the cell's metabolism, which enables them to induce oncogenic transformation in rodent cells. The E1A proteins modulate transcription by interacting both with gene‐specific and general cellular transcription factors. Various members of the AP‐1 and ATF/CREB families of transcription factors are targets for E1A‐dependent regulation, including cJun, the protein (...) product of the c‐jun proto‐oncogene. The E1A proteins modulate cJun‐dependent transcription both positively and negatively, and affect the activity as well as the expression levels of cJun. By increasing the phosphorylation status of cJun, E1A can stimulate transcription regulated by cJun/ATF2 heterodimers. In contrast, E1A inhibits the expression of various metalloproteases by interfering with the DNA‐binding capacity of cJun/cJun and cJun/cFos dimers, which might involve the association of E1A with the putative transcriptional coactivator p300. Since the ability of E1A to alter cJun‐dependent transcription correlates with its transforming capacity, interference with cJundependent transcription may be an essential step in E1A‐induced transformation. (shrink)

Two separate regulatory regimes govern research with adults who lack capacity to consent in England and Wales: the Mental Capacity Act (MCA) 2005 and the Medicines for Human Use (Clinical Trials) Regulations 2004 (“the Regulations”). A service evaluation was conducted to investigate how research ethics committees (RECs) are interpreting the requirements. With the use of a coding scheme and qualitative software, a sample of REC decision letters where applicants indicated that their project involved adults who lacked mental capacity was analysed. (...) The analysis focuses on 45 letters about projects covered by the MCA and 12 letters about projects covered by the Regulations. The legal requirements for involving incapacitated adults in research were not consistently interpreted correctly. Letters often lacked explicitness and clarity. Neither consent nor assent from third parties is a legally valid concept for purposes of the MCA, yet they were suggested or endorsed in 10 post-MCA letters, and there was evidence of confusion about the consultee processes. The correct terms were also not consistently used in relation to clinical trials. Inappropriate use of terms such as “relative” had the potential to exclude people eligible to be consulted. Unless the correct terms and legal concepts are used in research projects, there is potential for confusion and for exclusion of people who are eligible to be consulted about involvement of adults who lack capacity. Improved clarity, explicitness and accuracy are needed when submitting and reviewing applications for ethical review of research in this area. (shrink)

From a gender perspective, female immigrant domestic caregivers have been particularly impacted during the COVID-19 pandemic: first, as female immigrants, and second, due to their work within the domestic care sector, which has been so badly affected in this pandemic. This study investigates the emotions and experiences of 15 female Latin American immigrant domestic workers, caregivers in five Andalusian cities who were cohabiting with their employees/patients during the COVID-19 pandemic lockdown, using qualitative research through in-depth interviews and life stories. The (...) results show the moral debt accrued by the caregivers with the family who employ them, while worsening the physical and psychological health of many of the caregivers, due to both work overload and fear of the global pandemic. (shrink)

RESUMEN. En este artículo se analiza (y cuestiona) la tesis de la vulnerabilidad de la jurista estadounidense Martha A. Fineman. El trabajo se estructura en cinco apartados en los que el paradigma de Fineman es sucesivamente contextualizado, proyectado sobre la jurisprudencia del TEDH y comparado con otras contribuciones críticas al Derecho antidiscriminatorio. El trabajo finaliza con una breve conclusión en la que, aun reconociendo la validez del diagnóstico y la loable finalidad que mueve la teoría de Fineman, pone en duda (...) la virtualidad de la misma como inspiración de un nuevo y necesario concepto de igualdad jurídica. ABSTRACT. This article analyzes (and argues) the American legal scholar Martha A. Fineman’s thesis about vulnerability. It is divided into five sections in which Fineman’s paradigm is successively contextualized, projected to the ECtHR cases on vulnerability and compared with other critical contributions to Antidiscrimination Law. It ends with a brief conclusion that, while recognizing the validity of the diagnosis and the laudable purpose that moves Fineman’s theory, it is critical about taking it as inspiration for a new and necessary concept of legal equality. (shrink)